Andre Harriman-Annous was born on 28 December 2007 in Barnet, London, to a Nigerian mother and a Ghanaian father. He began playing football at the age of five with local club Whetstone Wanderers and spent a brief spell in Tottenham's pre-academy before joining Arsenal's academy in 2016, the club he supported growing up.
Harriman-Annous developed through Arsenal's youth ranks alongside a well-regarded group of academy players. During the 2024–25 season he featured across Premier League 2, the FA Youth Cup, and the UEFA Youth League, contributing goals along the way. His performances earned him first-team training opportunities in February 2025, and he made his senior debut in a pre-season friendly against Newcastle in Singapore in the summer of 2025, shortly after which he signed his first professional contract.
His professional debut came on 29 October 2025, when he started Arsenal's EFL Cup tie against Brighton & Hove Albion. He played 77 minutes as Arsenal won 2–0, marking a significant early step in his senior career.
Primarily a striker, Harriman-Annous also has experience in attacking midfield and out wide, giving him versatility across the front line. Arsenal continue to develop him as part of the club's first-team setup.
On the international front, Harriman-Annous is a youth international for England, receiving his first call-up at under-18 level in May 2025. He is also reportedly eligible to represent Nigeria, Ghana, and Lebanon through his parents.